290 research outputs found

    Exploiting the Parallelism Exposed by Partial Evaluation

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    We describe an approach to parallel compilation that seeks to harness the vast amount of fine-grain parallelism that is exposed through partial evaluation of numerically-intensive scientific programs. We have constructed a compiler for the Supercomputer Toolkit parallel processor that uses partial evaluation to break down data abstractions and program structure, producing huge basic blocks that contain large amounts of fine-grain parallelism. We show that this fine-grain prarllelism can be effectively utilized even on coarse-grain parallel architectures by selectively grouping operations together so as to adjust the parallelism grain-size to match the inter-processor communication capabilities of the target architecture

    Towards Intelligent Structures: Active Control of Buckling

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    The buckling of compressively-loaded members is one of the most important factors limiting the overall strength and stability of a structure. I have developed novel techniques for using active control to wiggle a structural element in such a way that buckling is prevented. I present the results of analysis, simulation, and experimentation to show that buckling can be prevented through computer-controlled adjustment of dynamical behavior.sI have constructed a small-scale railroad-style truss bridge that contains compressive members that actively resist buckling through the use of piezo-electric actuators. I have also constructed a prototype actively controlled column in which the control forces are applied by tendons, as well as a composite steel column that incorporates piezo-ceramic actuators that are used to counteract buckling. Active control of buckling allows this composite column to support 5.6 times more load than would otherwise be possible.sThese techniques promise to lead to intelligent physical structures that are both stronger and lighter than would otherwise be possible

    Composition of the L5 Mars Trojans: Neighbors, not Siblings

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    Mars is the only terrestrial planet known to have Tro jan (co-orbiting) asteroids, with a confirmed population of at least 4 objects. The origin of these objects is not known; while several have orbits that are stable on solar-system timescales, work by Rivkin et al. (2003) showed they have compositions that suggest separate origins from one another. We have obtained infrared (0.8-2.5 micron) spectroscopy of the two largest L5 Mars Tro jans, and confirm and extend the results of Rivkin et al. (2003). We suggest that the differentiated angrite meteorites are good spectral analogs for 5261 Eureka, the largest Mars Trojan. Meteorite analogs for 101429 1998 VF31 are more varied and include primitive achondrites and mesosiderites.Comment: 14 manuscript pages, 1 table, 6 figures. To be published in Icarus. See companion paper 0709.1921 by Trilling et a

    Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop

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    BACKGROUND: The randomised controlled trial is widely considered to be the gold standard study for comparing the effectiveness of health interventions. Central to its design is a calculation of the number of participants needed (the sample size) for the trial. The sample size is typically calculated by specifying the magnitude of the difference in the primary outcome between the intervention effects for the population of interest. This difference is called the 'target difference' and should be appropriate for the principal estimand of interest and determined by the primary aim of the study. The target difference between treatments should be considered realistic and/or important by one or more key stakeholder groups. OBJECTIVE: The objective of the report is to provide practical help on the choice of target difference used in the sample size calculation for a randomised controlled trial for researchers and funder representatives. METHODS: The Difference ELicitation in TriAls2 (DELTA2) recommendations and advice were developed through a five-stage process, which included two literature reviews of existing funder guidance and recent methodological literature; a Delphi process to engage with a wider group of stakeholders; a 2-day workshop; and finalising the core document. RESULTS: Advice is provided for definitive trials (Phase III/IV studies). Methods for choosing the target difference are reviewed. To aid those new to the topic, and to encourage better practice, 10 recommendations are made regarding choosing the target difference and undertaking a sample size calculation. Recommended reporting items for trial proposal, protocols and results papers under the conventional approach are also provided. Case studies reflecting different trial designs and covering different conditions are provided. Alternative trial designs and methods for choosing the sample size are also briefly considered. CONCLUSIONS: Choosing an appropriate sample size is crucial if a study is to inform clinical practice. The number of patients recruited into the trial needs to be sufficient to answer the objectives; however, the number should not be higher than necessary to avoid unnecessary burden on patients and wasting precious resources. The choice of the target difference is a key part of this process under the conventional approach to sample size calculations. This document provides advice and recommendations to improve practice and reporting regarding this aspect of trial design. Future work could extend the work to address other less common approaches to the sample size calculations, particularly in terms of appropriate reporting items. FUNDING: Funded by the Medical Research Council (MRC) UK and the National Institute for Health Research as part of the MRC-National Institute for Health Research Methodology Research programme

    US Cosmic Visions: New Ideas in Dark Matter 2017: Community Report

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    This white paper summarizes the workshop "U.S. Cosmic Visions: New Ideas in Dark Matter" held at University of Maryland on March 23-25, 2017.Comment: 102 pages + reference
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